Excess, insoluble amyloid beta protein (A beta) contributes to AD. How Excess Iron Raises Your Risk for Alzheimer’s, Trans Fats Linked to Increased Risk for Alzheimer’s, Journal of Alzheimer’s Disease January 13, 2020 [Epub ahead of print], Workshop on Non-Clinical Safety Evaluation of Preventive Vaccines: Recent Advances and Regulatory Considerations, December 2, 2002 (PDF), Page 4, Deutsches Ärzteblatt International 2017 Sep; 114(39): 653–659, Conclusion, Journal of Research in Medical Sciences 2018; 23: 51, Introduction, Journal of Trace Elements in Medicine and Biology March 2020; 58: 126444, Deutsches Ärzteblatt International 2017 Sep; 114(39): 653–659, Environmental, Occupational and Treatment-Related Exposure, Journal of Trace Elements in Medicine and Biology March 2020; 58: 126444, Introduction, Journal of Trace Elements in Medicine and Biology March 2020; 58: 126444, Methods, Deutsches Ärzteblatt International 2017 Sep; 114(39): 653–659, Deutsches Ärzteblatt International 2017 Sep; 114(39): 653–659, Neurotoxicity of Aluminum, Journal of Research in Medical Sciences 2018; 23: 51, Scandal-Ridden OPCW Now Using Twitter’s ‘Hide Replies’ Function, They Are Coming To Take You Away (Ha, Ha, Ho, Ho), Van Morrison’s Delightful New Politically Incorrect Album, Tucker Carlson Interviews Dr. Peter McCullough on Worldwide Conspiracy To Suppress Existing Drugs That Effectively Treat Covid Patients in Favor of ‘Vaccines’. When I read that I was kind of pulling my hairs out [thinking] ‘So, this is your indisputable evidence of safety?’ These documents never made it to mainstream media. This site needs JavaScript to work properly. Along with these essential metals, there are other metals that we are exposed to through things such as food. Aluminum is a neurotoxin, so it affects the nervous system and the brain. An aluminum-based rat model for Alzheimer's disease exhibits oxidative damage, inhibition of PP2A activity, hyperphosphorylated tau, and granulovacuolar degeneration. As noted in the Journal of Trace Elements in Medicine and Biology study,23 the “safety” limit for aluminum is not weight dependent. Aluminium found in food, cosmetics and medicines could be poisoning our brains and causing Alzheimer’s disease, a professor has claimed. Effect of aluminum on the blood-brain barrier permeability in acute and chronically hyperglycemic rats. Silica is needed for many functions in the body. The human body has the capability of excreting aluminum, but if it is deposited in excessive amounts that cannot be handled by the body, it gets deposi… However, no beneficial role of aluminum has ever been elucidated, and its presence is in no way evidence of benefit. In addition, modeling the time to clear aluminum from the body using Priest’s equation estimates that for this schedule a child will be over the safe level of aluminum in the body for 149 days from birth to 7 months, constituting about 70 % of days in this period. The blood-brain barrier is efficient at blocking the passage of aluminum into the brain 3,11; however, this barrier may not be as well developed in preterm infants.Because preterm infants are known to have immature renal function, Bishop et al 12 were concerned about aluminum toxicity in preterm infants receiving parenteral nutrition. Aluminum Toxicity: 4 Ways to Detox Your Brain & Body Aluminum Particulates Are Receptive To Low Frequencies Which Produce: Brain Fog Low Energy Dizziness Fatigue Ringing In Ears Anxiety Irritation Anger DEPRESSION ————————— Aluminum Toxicity: 4 Ways to Detox Your Brain & Body The Truth About Cancer - thetruthaboutcancer.com According to the Alzheimer’s Association of… Bethesda, MD 20894, Copyright The researchers point out that previous efforts to assess the aluminum burden created by vaccines were based on “whole-body clearance rates estimated from a study involving a single human subject.”. Biol Trace Elem Res. Dr. Joseph Mercola One of the first studies of its kind conducted in 1992 showed the accessibility for aluminum to cross the blood-brain barrier posing its greatest physical threat on the human body. As noted in this paper:26, “In addition to inducing oxidative stress and binding to negatively charged membrane structures in neurons, aluminum is able to modify hippocampal calcium signal pathways that are crucial to neuronal plasticity and, hence, to memory. Fernandes RM, Nascimento PC, Martins MK, Aragão WAB, Rivera LFS, Bittencourt LO, Cartágenes SC, Crespo-Lopez ME, do Socorro Ferraz Maia C, Lima RR. It remains unclear whether this is a cause or an effect of the disease. 2007 Sep;101(9):1275-84. doi: 10.1016/j.jinorgbio.2007.06.001. This scientist is raising the alarm about all these things becoming more prevalent in the ecosystem. Aluminum shows a strong positive effect on the activity of succinate dehydrogenase from rat brain. Baranauskaite J, Sadauskiene I, Liekis A, Kasauskas A, Lazauskas R, Zlabiene U, Masteikova R, Kopustinskiene DM, Bernatoniene J. Molecules. Aluminum exposure through the diet: metal levels in AbetaPP transgenic mice, a model for Alzheimer's disease. Developmental Effects. Unable to load your collection due to an error, Unable to load your delegates due to an error. It is proven that aluminum is linked to “Medically, proper organ, cellular and body aluminum detoxification appears to be of ever-increasing importance: Aluminum has been found in the brains of patients with Parkinson’s Disease, Alzheimer’s disease, epilepsy, and autism. Arch Toxicol 1999;73:419-426. Privacy, Help The use of Aluminum Utensils is associated with the worsening of the edema. While independent research in this field is prevented the questions concerning human toxicity remain unanswered. This occurs at 2 months, when four recommended vaccinations containing aluminum are simultaneously administered. Epub 2006 Jun 16. Studies show that toxic metals contribute to brain diseases by producing oxidative stress and aluminum is one of the worst offenders. Aluminium Induced Disease in Subjects with and without Renal Failure—Does It Help Us Understand the Role of Aluminium in Alzheimer’s Disease?. “Indeed, aluminum is known to increase the leakiness of epithelial and endothelial barriers and in doing so could concomitantly increase the passage of aluminum from the blood to the brain,” Exley writes.9. 2021 May;476(5):2233-2249. doi: 10.1007/s11010-021-04079-4. Usual human exposure is primarily dietary. Buy New $22.49 Microscopic investigation of the cerebral and cerebellar cortex showed distinct changes due to the effect of celphos. Epub 2007 Jun 12. Aluminum promotes formation and accumulation of insoluble A beta and hyperphosphorylated tau. The body is able to tolerate these metals in small amounts by clearing through the kidneys. Decreased renal function increases human risk of Al-induced accumulation and toxicity. The potential for significant Al absorption from the nasal cavity and direct distribution into the brain should be further investigated. Kücük M(1), Kalayci RB, Cevik A, Elmas I, Kaya M. Author information: (1)Department of Physiology of Istanbul Medical Faculty, Institute for Experimental Medicine and Research, Istanbul University, Turkey. Dr. Joseph Mercola Nayak P, Chatterjee AK. My comments above were one of the reasons the self-appointed global arbiter of fake news, NewsGuard, refused to give us “green” status as a site that follows “basic standards of accuracy and accountability.” In other words, our reporting of aluminum hazards was deemed “fake news.”, Not only were my earlier reports based on published science, but now we have yet another study,1 published in the Journal of Alzheimer’s Disease, strongly linking aluminum exposure to AD. Aluminum compounds occur naturally in the environment and in food, but very little ingested aluminum is absorbed through the intestines. Still, aluminum appears to be a significant concern that cannot be overlooked, especially where vaccines are concerned. Accessibility Biochem Int. As reported by SciTech Daily:2. It is present in the environment combined with other elements such as oxygen, silicon, and fluorine.Exposure to aluminum is usually not harmful, but exposure to high levels can cause serious health problems. [2] Due to its This is because the metal compound is present in a majority of fizzy drinks, wine, tea, malt drinks, cosmetics, toothpaste, antiperspirants, sunscreen, cocoa, processed foods, vaccines, antacids, and even drugs such as aspirin. To gain a better understanding of the link between aluminum exposure and beta-amyloid generation, the researchers examined the brain tissue of donors diagnosed with familial Alzheimer’s disease who also had a specific gene mutation known to increase levels of amyloid-beta, leading to early onset and more aggressive disease. “Indeed, aluminum is known to increase the leakiness of epithelial and endothelial barriers and in doing so could concomitantly increase the passage of aluminum from the blood to the brain,” Exley writes. Epub 2021 Feb 11. I’ve also warned that vaccines are a significant source of such exposure, and may be one of the worst, since by injecting it, the aluminum bypasses your body’s natural filtering and detoxification systems. In it, Exley (who also co-authored the featured Journal of Alzheimer’s Disease study above) wrote:6, “The aluminum industry is a pillar of the developed and developing world and irrespective of the tyranny of human exposure to aluminum it cannot be challenged without significant consequences for businesses, economies, and governments …. In December 2019, The Highwire reported14 the findings of a study15 published in the Journal of Trace Elements in Medicine and Biology, which found the U.S. Centers for Disease Control and Prevention’s childhood vaccine schedule — when adjusted for bodyweight — exposes children to a level of aluminum that is 15.9 times higher than the recommended “safe” level. 2006 Sep;52(2):275-92. doi: 10.1016/j.brainresrev.2006.04.003. Here’s how to fight back. Here, the authors again note that “it is widely accepted that [aluminum] is a recognized neurotoxin, which could cause neurodegeneration.” They also point out that aluminum “affects more than 200 important biological reactions and causes negative effects on [the] central nervous system.”, Aluminum Detected in Organs a Year After Vaccination. When welders work with aluminum, if the proper safety precautions aren’t taken, the aluminum dust will go directly into the lungs, into the bloodstream, through bones, and also into the brain. Neuroprotective potential of Malva neglecta is mediated via down-regulation of cholinesterase and modulation of oxidative stress markers. Evidence is growing that a host of chronic illnesses of unknown cause that are difficult to diagnose such as PANDAS/PANS, chronic fatigue syndrome may at least in part be due to vaccine aluminum intolerance. Cell Mol Biol (Noisy-le-grand). Hafez HA, Kamel MA, Osman MY, Osman HM, Elblehi SS, Mahmoud SA. It is known that aluminum displaces … Best Price: $7.40 ‘One could envisage increased amyloid-beta in brain tissue as a response to high levels of aluminum content, or that aluminum fosters the accumulation of amyloid-beta,’ said Dr. Exley. Tsunoda M, Sharma RP. No, it’s been ASSUMED safe.”, Industry Propaganda and Political Interference, The propaganda responsible for hiding the dangers of aluminum was addressed in a 2014 review article5 in the journal Frontiers of Neurology. It is suspected that excessive exposure to aluminum can cause neurological damage. Fat for Fuel: A Revolu... Importantly, aluminum has the ability to cross the blood-brain-barrier, so any aluminum in the blood can be transported into the brain. Problems only arise once a certain threshold is reached, and even then, its role in disease is rarely if ever investigated. Epub 2020 Jun 20. Evaluation of Cerebellar Function and Integrity of Adult Rats After Long-Term Exposure to Aluminum at Equivalent Urban Region Consumption Concentrations. As reported by SciTech Daily:3, “The results strongly suggest that genetic predispositions known to increase amyloid-beta in brain tissue also predispose individuals to accumulate and retain aluminum in brain tissue …. The toxicity of Al to plants, aquatic life and humans may share common mechanisms, including disruption of the inositol phosphate system and Ca regulation. Aluminum is a trivalent cation found in its ionic form in most kinds of animal and plant tissues and in natural waters everywhere. Exley points out that one of the most significant factors driving complacency about aluminum exposure is the aluminum industry’s insistence that, since it’s everywhere and found in virtually everybody,7 it must be harmless if not essential — we just haven’t figured out how it benefits us yet. Vaccine Schedule Overexposes Infants to Aluminum. Brain Al entry from blood may involve transferrin-receptor mediated endocytosis and a more rapid process transporting small molecular weight Al species. Clearly, Alzheimer’s and autism are not caused by a single factor. Importantly, infants also have immature renal function, which will inhibit their ability to filter and excrete toxins in the first place. No aluminum, no AD. Essentially, the rate of delivery of Al3+(aq) to target ligands must be sufficient to overcome the inherent robustness of systems that are under attack. (as of 09:53 EST - Details) 2000 Jun;46(4):721-30. In the Journal of Trace Elements in Medicine and Biology study,19 the researchers used several different models in an effort to estimate the expected acute and long-term whole-body accumulation of aluminum in children following one of the three possible vaccine schedules: The CDC’s standard schedule resulted in the greatest expected aluminum burden in all model assumptions, while Thomas’ schedule resulted in the lowest. Aluminum is environmentally ubiquitous, providing human exposure. The modified CDC schedule assumes the same vaccinations at the same times as the CDC schedule, but like the Vaccine Friendly Plan it assumes a lower dose aluminum DTap vaccine, and also combines the ActHib (containing no Al) with low aluminum DTap or PVC13 so that the aluminum adjuvant in the aluminum containing vaccine (ACV) activates an immune response for the ActHib vaccine. Previous article by Joseph Mercola: Daily Aspirin — Healthy or Harmful? It should be expected that most aluminum retained in the body of infants comes from vaccinations combined with the levels of exposure from other exposures to manifest health risks from total exposure, making the timing and total aluminum content of different vaccine schedules an important consideration.”, CDC Vaccine Schedule Exceeds Aluminum Limit for Adults. ‘Either way, the new research confirms my resolve that within the normal lifespan of humans, there would not be any AD if there were no aluminum in the brain tissue. Why Aluminum Toxicity Flies Under the Radar. 1, this stimulation is a function of the metal ion concentration. Aluminum induced oxidative events and its relation to inflammation: a role for the metal in Alzheimer's disease. Quantities that are not eliminated appear to have an affinity for endothelial cells lining cerebral blood vessels and possibly the brain, with likely downstream pro-inflammatory and pathogenic effects. Effects of Al on the activity of Krebs cycle enzymes. It was commoner in males from both rural and urban areas and in the 21-30 year age group. Most of this aluminum accumulates in the bones, but about 1% of residual aluminum is estimated to accumulate in the brain. Yet another factor that helps hide the influence of aluminum in disease is the fact that it acts on many different pathways and acts as a substitute for essential minerals, so aluminum toxicity doesn’t have one specific hallmark. It’s just a lie perpetuated over and over again; that we’ve been using these things for over nine decades and it’s been proven safe. Vaccine passports have arrived in New York. 1. Our calculations confirm that for the CDC schedule, infants up to six months of life receive most of their metabolically available aluminum from vaccines. This drops the maximum level of exposure to about 60 % of the original CDC plan with (from 15.9 to 9.3) and drops days above the estimated safe limit in the first 7 months from 70 % of days to 26 % and in the first 2 years from 24 % of days to 8 %. One such environmental factor is human exposure to aluminium and aluminium has been shown to be present in brain tissue in sporadic Alzheimer’s disease. Modulation of tumor necrosis factor alpha expression in mouse brain after exposure to aluminum in drinking water. Injections of Al to animals produce behavioral, neuropathological and neurochemical changes that partially model AD. If you think you have been exposed to high levels of aluminum, contact your doctor. This is clearly an unwise comparison, as only 0.1% of orally ingested aluminum is absorbed and made bioavailable from the gastrointestinal tract.17,18. Bharathi, Shamasundar NM, Sathyanarayana Rao TS, Dhanunjaya Naidu M, Ravid R, Rao KS. Aluminium phosphide (Celphos) was used by 239 victims (75.40% of the total) and was used in 69.03% of male and 30.96% of female cases. Rao KS(1). What’s more, they used an aluminum citrate solution that is not used in vaccines, which may affect the excretion rate. There is prolonged retention of a fraction of Al that enters the brain, suggesting the potential for accumulation with repeated exposure. J Inorg Biochem. Elevated aluminum content has been found in the brains of persons with Alzheimer's disease. We have made the first ever measurements of aluminium in brain tissue from 12 donors diagnosed with familial Alzheimer’s disease. Brain Research Bulletin 2001, 55 (2) , 229-234. Aluminum in the diet and Alzheimer's disease: from current epidemiology to possible disease-modifying treatment. Toxicology. Aluminum present in medicines, cosmetics, and food could be slowly poisoning our brains and even causing Alzheimer's disease. Effects of aluminum exposure on brain glutamate and GABA system: an experimental study in rats. Your diet and lifestyle play significant roles, as do other toxic exposures. According to the authors:22. Exley also points out aluminum can damage your brain function by: A 2010 paper10 also pointed out that aluminum salts “can increase levels of glial activation, inflammatory cytokines and amyloid precursor protein within the brain,” and that “Both normal brain aging and to a greater extent, Alzheimer’s disease are associated with elevated basal levels of markers for inflammation.”. Importantly, aluminum has the ability to cross the blood-brain-barrier, so any aluminum in the blood can be transported into the brain. National Library of Medicine 1992 Oct;28(1):51-6. Aluminium incorporation into the brain of rat fetuses and sucklings. The health hazards of aluminum are also addressed in a 2017 scientific review25 published in the German journal, Deutsches Ärzteblatt International, which also reviews the threshold values associated with various types of exposure. Careers. DOI: 10.1016/S0361-9230(01)00509-3. Paul Altmann. 2008 Jul 30;249(2-3):214-9. doi: 10.1016/j.tox.2008.05.004. Aluminum has the ability to produce neurotoxicity by many mechanisms. 2010;20(1):17-30. doi: 10.3233/JAD-2009-1340. As noted by Tomljenovic in that interview: “A document4 from 2002 from the U.S. Food and Drug Administration (FDA) … discussing the assessment of vaccine ingredients … and testing specifically in animal models … stated that the routine toxicity studies in animals with vaccine ingredients have not been conducted because it was assumed that these ingredients are safe. It shows that aluminum and amyloid-beta are intimately woven in the neuropathology,’ explained lead investigator Christopher Exley, PhD, Birchall Centre, Lennard-Jones Laboratories, Keele University, Staffordshire, UK.”, The Association Between Aluminum and Amyloid-Beta. Upon analysis, the researchers found that aluminum was present in the same areas of the brain as the tangles of protein that appear in the early stages of Alzheimer's. Aluminum has the ability to produce neurotoxicity by many mechanisms. [1] It is the third most prevalent element and the most abundant metal in the earth's crust, representing approximately 8% of total mineral components. To some extent, Al mimics the deficit of cortical cholinergic neurotransmission seen in AD. “The potential for aluminum to interact with and to influence so many biochemical pathways means that the symptoms of its toxicity could be deficiency or sufficiency, agonistic or protagonistic, and any combination of these and other physiology-based events,” Exley writes, adding:8. The study also found a high degree of co-location with the amyloid-beta protein, which leads to early onset of the disease. As revealed in my 2015 interview with Dr. Lucija Tomljenovic, featured in “How Vaccine Adjuvants Affect Your Brain,” when aluminum was first approved for use in vaccines, some 95 years ago, it was approved based on its efficacy. There has been and there continues to be systematic attempts by the aluminum industry to suppress research on aluminum and human health. The study also found a high degree of co-location with the amyloid-beta protein, which leads to early onset of the disease. There is … Frisardi V, Solfrizzi V, Capurso C, Kehoe PG, Imbimbo BP, Santamato A, Dellegrazie F, Seripa D, Pilotto A, Capurso A, Panza F. J Alzheimers Dis. Even the total allowable limit was based on efficacy data, not safety data. In achieving this threshold either aluminum must accumulate over time within a particular compartment or possibly the administration of a single dose of aluminum could achieve such a threshold instantaneously. 9 Total aluminum exposure is affected by the aluminum amount in individual vaccines and the timing of repeated vaccinations in the first two years of life. Look into L-Theanine. Exley also notes that aluminum is rarely acutely toxic, which adds to the complacency problem. Ameliorative effects of astaxanthin on brain tissues of alzheimer's disease-like model: cross talk between neuronal-specific microRNA-124 and related pathways. They simply assumed it was safe. Aluminum has been safely chelated using EDTA, with associated beneficial effects … Epub 2008 May 17. Edema is caused by a series of factors among them is … This research provides conclusive evidence for concern, which means it would be foolish in the extreme to pretend that injecting infants and young children with aluminum-containing vaccines is harmless. Can we really justify loading infants up with aluminum at doses that are toxic even to an adult? However, researchers did not notice any adverse effects of aluminum from the deodorants on the nervous system. How Aluminum Affects the Brain — One way aluminum damages the brain is by dramatically increasing oxidative stress — that is, accumulation of free radicals and lipid peroxidation products in the brain. 2021 May 12. doi: 10.1007/s11011-021-00749-w. Online ahead of print. Findings of the neurotoxic effects of aluminum was published by The New England Journal of Medicine in 1997. Importantly, as noted in the Journal of Research in Medical Sciences, aluminum has been shown to “cause mitochondrial dysfunction and depletion of adenine-triphosphate (ATP),”13 which sets the stage for virtually any chronic disease, not just neurodegenerative diseases. “Adjusting the safe dose limit based on a child’s weight at these ages therefore results in doses that far exceed the estimated safe limit of acute toxicity,” the authors warn,24 adding that “on all days of injection the safe limit for a child is exceeded for all three schedules; this points to acute toxicity …. Al is a neurotoxicant in animals and humans. Aluminum promotes formation and accumulation of insoluble A beta and hyperphosphorylated tau. Epub 2021 Feb 11. Deficit of cortical cholinergic neurotransmission seen in AD have not resolved the controversy in! 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